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But adding a Drug Affinity Complex (DAC) further alters its propertiesdramatically

At the molecular level, curcumin modulates key pathwaysfrom inhibiting NF-B and proinflammatory cytokines to activating Nrf2-driven antioxidant defenses and disrupting microbial biofilmsthereby breaking the cycle of inflammation and oxidative stress that underlies conditions such as periodontitis, mucositis, and oral lesions (Indriyani and Nuraeny, 2025

In addition, KI treatment of TAD-2 cells increased ROS production and it dramatically increased the level of thiobarbituric acid reactive substances, being the index of lipid peroxidation [175]

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The resulting microsomal pellets were resuspended in 100 L PBS and used to determine total heme-oxygenase (HO 1/2) protein activity

He identified tarsal tunnel syndrome that had been missed for years