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Therefore, GH excess may be an important promoter of diabetic nephropathy in poorly controlled T1DM patients

The concept of direct GH action on glomerular cells is supported by studies in transgenic mice overexpressing human or bovine GH showing progressive glomerulosclerosis, whereas IGF-1 overexpressing mice lack glomerular changes [14]

Although extensive research has predominantly focused on the role of CACNA1A in neurological disorders, emerging evidence indicates its regulatory function in various cancers [20, 21]

In this study, 20 tissue samples from ovarian cancer patients, as well as 20 samples of normal ovarian tissue from patients with benign gynecological diseases were collected during surgery

Relationship of opioid use and dosage levels to fractures in older chronic pain patients

Water retention: Slight puffiness in the hands or feet, most common during the escalation phase and typically self-limiting