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In conclusion, treatment with EGCG at high doses or for prolonged duration may have adverse effects, and the above data suggest that the boundary between protective and toxic doses of EGCG may be narrow

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7 Conclusions and perspectives In recent years, with the increasing exploration of the intestinal microenvironment, there is growing evidence that dysbiosis of the gut microbiota and disorders of iron metabolism are closely associated with the onset and progression of IBD

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