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HIF-1 allows tumor cells to survive in the absence of oxygen, activating the transcription of glycolytic enzymes, glucose transporters, and vascular endothelial growth factors (Zhong et al., 1999)

For instance, baicalin-loaded liposomes (BCL-LPs) fabricated via this technology exhibited superior drug encapsulation and bioavailability in zebrafish, significantly augmenting anti-tumor and anti-inflammatory efficacy ( The Zebrafish Entrapment By Restriction Array (ZEBRA) device, introduced by Bischel et al., further enables high-throughput live imaging of zebrafish embryos ( Tg(mpx:dendra2) zebrafish, the device validated leukotriene B4 (LTB4)-induced neutrophil migration to the tail fin and its inhibition by LY294002, demonstrating its utility for real-time analysis of immune cell dynamics (Xie et al., 2020)

FAQs Glutathione is a powerful antioxidant that helps reduce oxidative stress

5A peptide induces macrophages cholesterol efflux via ABCA1-mediated mechanism both in vivo and vitro, and reduces atherosclerosis in Apo E-absent mice 150

OBrien MK, Botonis OK, Larkin E, Carpenter J, Martin-Harris B, Maronati R, Lee K, Cherney LR, Hutchison B, Xu S, Rogers JA, Jayaraman A (2021) Advanced machine learning tools to monitor biomarkers of dysphagia: a wearable sensor proof-of-concept study

Dutt, S., Hamza, I