foxo4 dri senolytic 2023 2024 foxo4-dri peptide mouse study Molecular modelling of the FOXO4-TP53 interaction to design peptides for the elimination of senescent cancer cells FOXO4-DRI Peptide Inhibitors Targeting FOXO4-p53 Interactions

Peptide Inhibitors Targeting FOXO4 p53 Interactions and Inducing Senescent Cancer Cell specific Apoptosis Journal of Medicinal Chemistry Targeting Cellular Senescence in Aging and Age Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies Frontiers Senolytic Peptide FOXO4 DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Targeting the FOXO4 p53 axis by retro inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline Naunyn Schmiedeberg's Archives of Pharmacology Springer Nature Link

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