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It exists in two main forms: eumelanin (which is darker, usually brown or black) and pheomelanin (which is lighter, often yellow or red)

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Recent developments in spectroscopic editing methods have provided quantitative MRS approaches to measure challenging metabolites such as glycine (Gly), glutamine (Gln), glutamate (Glu), 2-hydroxyglutarate (2HG), cystathionine and glutathione (GSH), in addition to routine MRS based measurements of metabolites, such as N-acetylaspartate (NAA), choline (Cho), creatine (Cr), lactate (Lac), etc

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The question of whether having higher serum vitamin C concentrations provide additional antioxidant benefit has also been explored