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The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

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In summary, how to specifically inhibit the amino acid metabolism of tumor cells and immunosuppressive cells in the microenvironment, and enhance the amino acid metabolism of anti-tumor immune cells such as CD8 + T cells, is an urgent problem to be solved

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[DOI] [PMC free article] [PubMed] [Google Scholar] 420.Lin J., Sahakian D.C., De Morais S.M.F., Xu J.J., Polzer R.J., Winter S.M

This is where glutathione, a powerful pro-tumor nutrient that Harris has been studying, came into focus