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In order to develop more specific and less toxic inhibitors, there have been efforts to utilize interactions in the region of the active site of GGT that binds the cysteinylglycine moiety of GSH (13, 17)

For example, O 2 triggers the intracellular p38 MAPK and JNK pathways, promoting apoptosis while also generating other ROS (such as H 2 O 2 ) to further amplify oxidative damage [218]

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Tumors: Cancerous and noncancerous growths and tumors can develop on the nerves causing neuropathy

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