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In vitro and in vivo antioxidant potential of hydromethanolic extract of Phoenix dactylifera fruits

The authors were able to show increased damage to mitochondrial DNA in both idiopathic PD and in patients carrying the G2019S LRRK2 mutation, and found that mitochondrial DNA damage correlated with LRRK2 kinase activity

All these molecules are produced during the activity of peroxisomes, endoplasmic reticulum, proteasome, and mitochondria (PERM) [91]

Curr Opin Pharmacol 7:3559 Samuni Y, Goldstein S, Dean OM, Berk M (2013) The chemistry and biological activities of N -acetylcysteine

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