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Leptin, a hormone associated with hunger and metabolism, decreased with doses of 4 mg or greater at 24 weeks and 8 mg or greater at 48 weeks

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doi: 10.1177/10870547221110918 [DOI] [PMC free article] [PubMed] [Google Scholar] 147.Borge TC, Biele G, Papadopoulou E, Andersen LF, Jacka F, Eggesb M, et al

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Upon intravenous injection, the nanoreactors selectively accumulate in the tumor and nearly fully eradicated an aggressive osteosarcoma inside a mouse model