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Department of Tissue Engineering and Regenerative Medicine (DTERM), Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000 Cheras, Kuala Lumpur, Malaysia

found that treatment of WT mice with the exogenous depalmitoylation inhibitor Palm B was able to significantly increase synaptic postsynaptic density protein 95(PSD-95) levels by inhibiting PSD-95 depalmitoylation, which could reverse A-induced synaptic inhibition, but the same manipulation was not effective in PSD-95 knockout (KO) mice