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doi: 10.1126/scitranslmed.aan0241

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Phase 2b studies demonstrated tirzepatide produces HbA1c reductions of up to 2.4% versus placebo at 26 weeks (Thomas et al., 2021), with Phase 3 SURPASS trials confirming mean HbA1c reductions from baseline of 2.07 percentage points with tirzepatide 15 mg (treatment difference vs

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Rotate sites: Use a systematic rotation to prevent irritation or lipoatrophy

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