glutathione synthetase deficiency oxoproline Pyroglutamic Acidosis • LITFL • CCC Acid-base The Case | Severe high-anion
The Case Severe high anion gap metabolic acidosis Kidney International The glutamyl cycle. Step 1: Glutathione synthetase deficiency induces Download Scientific Diagram Inborn errors in the metabolism of glutathione Orphanet Journal of Rare Diseases Springer Nature Link Mutations in the glutathione synthetase gene cause 5oxoprolinuria Nature Genetics What is pyroglutamic acid (5oxoproline)? Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
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