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TA Instrument, New Castle, DE, USA) was used for the analysis of DSC data

452,453 In neurodegenerative diseases, neurotoxic substances from neuronal damage help to activate Drp1-mediated mitochondrial fission in microglia, down-regulate OXPHOS and ATP production with elevated ROS production, meanwhile motivating inflammasome formation

Curcuma Longa (Turmeric): Contains curcumin, which offers powerful anti-inflammatory and antioxidant benefits for full-body wellness

In contrast, previous studies have reported the use of plasma collected exclusively in sodium heparin tubes 67,68 , which is acceptable for determining oxalate in most clinical laboratories

Such results imply that metformin could aggravate tau pathology, potentially via the overactivation of AMPK and downstream GSK3, since excessive AMPK activity has been linked to tau aggregation in other models [181]

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