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The manufacturer is explicit about this: frozen tirzepatide must be discarded even after thawing

Design, Setting, and Participants A prospective follow-up study in 899 men and women who were free of dementia at baseline, had a median age of 76.0 years, and were followed up for a mean of 9.1 years for the development of all-cause dementia and Alzheimer disease

Acknowledgements This work was supported by the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre

JCI Insight 8 , e170419 (2023)

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For a class like the growth hormone peptides, the most valuable thing a clinician can learn is how to reason about it honestly : how a secretagogue differs from direct HGH therapy, how a GHRH analog differs from a ghrelin mimetic, how to read the limits of the evidence, how to interpret a regulatory map that ranges from FDA-approved to PCAC-rejected, and how to communicate realistic, months-long timelines without overpromising