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NETosis is an important neutrophil function that can promote liver metastasis of breast cancer and different pro-metastatic neutrophil populations are highly metabolically adaptable, which facilitates the formation of liver metastases (145)

However, in non-APL tumors, ATO faces a metabolic bottleneck that limits its efficacy, because a crucial aspect of ATOs pharmacological effects is that the parent compound is not the ultimate cytotoxic effector

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Sections were blocked in blocking buffer (1% BSA, 2% normal goat serum in PBS) for 1 h at 37C and incubated with primary antibodies overnight at 4C in a humid chamber and secondary antibodies at 37C for 1 h followed by mounting using ProLong Gold (Thermo Fisher Scientific)

A spreadsheet representation can also be found in Additional file 3

Das erhht die Fhigkeit, Fettsuren whrend des Trainings zu oxidieren, und verbessert die allgemeine Fettverbrennungskapazitt