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Effects of carnosine (Beta-Alanyl-L-Histidine) in an experimental rat model of acute kidney injury due to septic shock

H (400 MHz, MeOD): 4.62 (1 H, dd, J = 9.1, 4.9 Hz, H-4), 4.06 (1H, t, J = 6.4 Hz, H-1), 3.89 (1 H, d, J = 17.8 Hz, H-6 A or B ), 3.85 (1 H, d, J = 17.8 Hz, H-6 A or B ), 3.483.36 (2 H, m, PCH 2 ), 3.26 (1 H, d, J = 14.8 Hz, H-7 A or B ), 3.20 (1 H, d, J = 14.8 Hz, H-7 A or B ), 3.19 (2 H, d, J = 6.4 Hz, H-8), 3.10 (1 H, dd, J 14.0, 4.9 Hz, H-5 A or B ), 2.85 (1 H, dd, J = 14.0, 9.1 Hz, H-5 A or B ), 2.59 (2 H, t, J = 7.1 Hz, H-3), 2.332.22 (1 H, m, H-2 A or B ), 2.222.12 (1 H, m, H-2 A or B ),1.761.65 (2 H, m, CH 2 ), 1.651.51 (4 H, m, CH 2 )

However, it contains therapeutic potential in exploiting its pathways to overcome apoptosis resistance and augment immune response in cancer therapies (Baig et al

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F., El-Kalaawy A

doi: 10.14336/AD.2023.0312-1, [DOI] [PMC free article] [PubMed] [Google Scholar] 115.DeKroon RM, Osorio C, Robinette JB, Mocanu M, Winnik WM, Alzate O