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10.1002/bies.202000119 Summary Keywords cancer organoids, personalized therapy, extracellular matrix (ECM), decellularized matrix, ex vivo cancer models, drug screening Citation Varinelli L, Illescas O, Lorenc EJ, Battistessa D, Di Bella M, Zanutto S and Gariboldi M (2025) Organoids technology in cancer research: from basic applications to advanced ex vivo models