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Quality animal studies are needed, at least for molds responsible for severe adverse health effects, to develop RfDs/RfCs, ADI/TDI for both mold components (e.g., spores, hyphal fragments) and mycotoxins, especially following inhalation exposure

The meta-analysis showed that blood concentrations of oxidative glutathione (GSSG), malondialdehyde, homocysteine, S -adenosylhomocysteine, nitric oxide, and copper were higher in children with ASD than that of HC children

Hirooka T, Kaji T

Among NLP-positive patients, patients had significantly greater odds of having concomitant problem list documentation of NAFLD if Hispanic, seen by a gastroenterology provider or had documented components of metabolic syndrome (Figure)

Hypothesis: Prospective clinical and biopsy data will identify factors associated with severe liver disease outcomes in AATD