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R.BarrientosR

doi:10.1186/s12967-021-02742-4 Campagnolo N, Johnston S, Collatz A, Staines D, Marshall-Gradisnik S

77 LiN.ChenH.ChengY.XuF.RuanG.YingS.et al (2021)

a 2-year prospective study from the Northern Territory of Australia

Nevertheless, the homozygote mutant genotype leads to hyperhomocysteinemia only when plasma folate status is low in healthy subjects and in patients with cardiovascular disease, thus subjects with this MTHFR mutation may be sensitive to low folate intake (Christensen et al, 1997