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Curr Med Chem

Given sulforaphanes ability to activate multiple cytoprotective mechanisms, sulforaphane is emerging as a promising therapeutic for multiple neurodegenerative and neurodevelopmental disorders

The two Mtb RbpA residues (E17, R10) that interact with Fdx are colored in purple and indicated in the text

Accordingly, a marginal alteration in the intracellular concentration of GSH may not influence the catalytic activities of seleno-GPxs under in vivo conditions

doi:10.3892/etm.2019.8393 Capasso A

For example, the cleavage site may be too close to ordered structure in the target protein." The problem is especially severe for oligomeric proteins