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Current approaches of ferroptosis inhibitors as radioprotective therapeutics The emerging connections between IR and ferroptosis have generated excitement toward ferroptosis inhibitors as potential interventions to mitigate IR-induced tissue injury

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At the same time, it oxidizes nicotinamide adenine dinucleotide phosphate (NADPH)

Remarkably, some patient sera also contained antibodies capable of neutralizing pSYN seeding (forming of SYN aggregates) in vitro (99)

Notably, mitochondrial modulators such as metformin have demonstrated beneficial effects in diabetic wound models

doi: 10.1038/s41477-020-0605-7