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Delivery-mediated exosomal therapeutics in ischemia-reperfusion injury: advances, mechanisms, and future directions

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They uncovered a new type of cell death, whereby mitochondria move to the plasma membrane generating ROS, which in turn damages the plasma membrane leading to cell lysis, the type of lysis being termed mitoxyperilysis (Fig

Glutathione is an anti-oxidant thats naturally synthesised in our body

To evaluate whether mutants deficient in different glutathione-dependent enzymes are impacted by TMHT, we subjected cytosolic glutaredoxin mutants to TMHT (Figure 4C)

51, Issue 19, pp