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Additional research confirmed TB-500s actin-sequestering mechanism promotes cell motility at concentrations as low as 0.11.0 g/mL in cell culture models

reported the results of another phase 1 clinical study (NCT02942329) which aimed to investigate the efficacy of SHR-1210 (anti-PD-1 antibody) plus apatinib (VEGFR2 TKI) in refractory hepatocellular cancer (HCC), gastric cancer (GC), and esophagogastric junction cancer (EGJC) patients [97]