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NAD+ Preservation: Helps maintain higher NAD+ levels for cellular energy

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5-amino-1MQ did not inhibit SIRT1 concentrations ranging from 10 nM-300 M, and minor reduction in SIRT1 activity was observed with 600 M 5-amino-1MQ

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Importantly, NNMTi is highly selective and has no inhibitory effect on other SAM-dependent methyltransferases or NAD + salvage pathway enzymes

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SURMOUNT-CN reported about 17.5% at 52 weeks

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