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Computational screening of natural MtbDXR inhibitors for novel anti-tuberculosis compound discovery

In addition to glucose metabolism, lipid metabolism and amino acid metabolites, oxidative stress, iron metabolism, nitric oxide metabolism and other processes and metabolites are also closely related to psoriatic T cells, and then affect the progression of psoriasis (131133)

These molecules can further induce various transcription factors, like NF-B, STAT, p53, and activator protein-1 (AP-1) [9]

Interestingly, there is emerging evidence that TCAs may improve liver fibrosis and reduce portal hypertensive complications, a potential dual benefit that warrants further investigation [55, 56]

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(4) infectious lesions, in which a portion of the nervous system is destroyed or injured as a result of infection, for example, by an abscess or associated with infection by human immunodeficiency virus, herpes zoster, or herpes simplex virus or with Lyme disease, tuberculosis, syphilis