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Dipeptidyl peptidase Inhibitors (vildagliptin & sitagliptin) suppress breakdown of Glucagon like peptide1 (GLP-1) show great potential and are undergoing clinical testing
Severe bullous skin eruptions on checkpoint inhibitor therapyin most cases severe bullous lichenoid drug eruptions
doi: 10.1038/s41385-020-00368-1 42 NutmaEWillisonHMartinoGAmorS
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Where peptides show up globally Depending on the peptide and local rules, peptides are commonly discussed in five broad buckets: 1) Tissue-response & recovery research soft tissue and connective-tissue models gut/lining-related research models post-injury / post-procedure recovery discussions (often speculative online) 2) Inflammation & immune-pathway research experimental models looking at inflammatory signaling immune modulation research (highly context-dependent) 3) Skin, hair & cosmetics anti-aging skincare formulations collagen-support signaling in topical contexts skin texture/elasticity positioning (cosmetic claims vary by jurisdiction) 4) Brain & cognition research attention, memory, mental fatigue (research discussion varies widely in quality) stress-response pathways and behavioral research 5) Metabolism & appetite research weight-management research (specific peptide classes) blood sugar and insulin-related research (highly regulated categories) Reality check: for many peptides, evidence is still developing
master antioxidant, it works deep at the cellular level to help defend against oxidative stress
