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(2015) 10:e0123547

10.1016/j.it.2016.10.001 53

While much is currently known about APAP hepatotoxicity regarding its epidemiology, risk factors, pharmacology and toxicology, diagnostics and treatment modalities, there remains a plethora of scientific questions that should be answered in order to improve the understanding of molecular and sub-molecular relationships and pathways that may offer new therapeutics to tackle this curable yet potentially devastating event

I.Nature 449, 804810

55 These include the fatty liver index, NAFLD liver fat score, NAFLD ridge score, hepatic steatosis index, steatotest, visceral adiposity index, 56 triglycerides and glucose index, 57 lipid accumulation product