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This review article will cover up-to-date information about GABA-producing microorganisms isolated from human gut and food sources, explanation why those microorganisms produce GABA, food factors inducing gutGABA production, evidence suggesting GABA as a mediator linking between gut microbiota and mental health, including anxiety, depression, stress, epilepsy, autism spectrum disorder, and attention deficit hyperactivity disorder, and novel information regarding homocarnosine-a predominant brain peptide that is a putative downstream mediator of GABA in regulating brain functions

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Zhou Y, Danbolt NC

Impaired expression of inducible nitric oxide synthase reduces the production and release of inflammatory factors TNF-1, IL-6, IL-8, and NO

Nutritional support, preferably through enteral tube feeding rather than parenteral nutrition, should be prioritized when oral intake is inadequate