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No documented interactions with HRT, but women on estrogen-sensitive therapies should consult a provider

The usual frequency for intramuscular doses of B12 shots is every 10 days, followed by maintenance doses at varying intervals

A standard American diet (SAD diet) that we discussed being high in processed food and macronutrients, may be low in micronutrients and other essential nutrients from a lack of whole foods including plant foods

doi: 10.1038/nrc2817 [DOI] [PubMed] [Google Scholar] 24.Evangeliou A, Vlachonikolis I, Mihailidou H, Spilioti M, Skarpalezou A, Makaronas N, et al

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Fillers can have adverse effects, but these will depend on the filler