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The cAMP-mediated PKA pathway has been shown to promote tumor cell proliferation and progression also in multiple preclinical cancer models [18]

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Another AD marker, TAU, aggregates through heme oxygenase 1 overexpression and iron accumulation 194

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The downregulation of surface glutamate receptors triggered by hypoxia may be considered as a neuroprotective response in order to preserve neurons from glutamate receptor-mediated excitotoxicity

Gao SP, Zhang Y, Sun Q, Guo ZM, Zhang D, Zou XB (2024b) Enzyme-assisted patulin detoxification: recent applications and perspectives