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This conversion process can be less efficient, especially in individuals with certain health conditions or genetic variations

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Self-reported community protocols commonly describe once-daily dosing with on/off cycling, motivated partly by the absence of any long-term human safety data and partly by a community perception of diminishing returns or tolerance over continued use

J Biol Chem 250:14221426 Riley R, Haridas S, Wolfe KH, Lopes MR, Hittinger CT, Goker M, Salamov AA, Wisecaver JH, Long TM, Calvey CH et al (2016) Comparative genomics of biotechnologically important yeasts