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Topical anti-inflammatory activity of gedi leaves extract gel (Abelmoschus manihot L.) on carrageenan-induced paw edema in male wistar albino rat

Cannabis sativa Another study reported the anti-inflammatory potential of beta-caryophyllene, a sesquiterpene present in the Cannabis sativa L

This diversity complicates the development of broad-spectrum senomorphic therapies.31 Senomorphic compounds that work effectively in one tissue might not produce the same results in others, requiring tailored or tissue-specific therapies.199 Regulatory Hurdles: Senomorphic therapies, particularly those derived from natural compounds (eg, resveratrol, curcumin), may face challenges in regulatory approval

Unlike neurons, which primarily generate ATP through oxidative phosphorylation, astrocytes predominantly rely on glycolysis for energy production

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Drugs in this group include metformin and myoinositol (137)