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Description

Approximately 40% of CRC patients harbor KRAS mutations, which activate the RASRAFMEKERK signaling cascade [67]

b , Total GPX4 enzymatic activity (endogenous apo-GPX4 and transfected exogenous GFP-tagged-GPX4) of control HT1080 (pBP, no expression of GFP-tagged-GPX4) and HT1080 cells overexpressing GFP-GPX4 WT or GFP-GPX4 R152H