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10.1016/j.ejphar.2003.08.013 11 Belosic HalleZ.VlainicJ.DrmicD.StrinicD.LueticK.SucicM.et al (2017)

By reducing the activity of macrophages and impeding the infiltration of inflammatory elements into the brain parenchyma, bevacizumab contributes to a neuroprotective milieu (Genovese and Impellizzeri 2022)

However, targeting downstream effectors or co-factors of TGF- signaling, such as those that are only active during myofibroblast differentiation, may be a more successful approach