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For example, sulforaphane, an isothiocyanate common in Brassicaceae family, protects the mucous membrane of GIT from oxidative damage through the activation of the Nrf2-Keap1 system, upregulating the transcription of antioxidant enzymes (Yanaka, 2017)

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Autophagy 2022;18:18791897

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After exhaustion of the liver reserves, pernicious anemia, symptomatic psychoses and funicular spinal diseases occur, which initially manifest themselves in paresthesia with a tingling sensation and weakened muscle tone, accompanied by depressive moods