glutathione reaction with cysteine Frontiers S-glutathionylation cycle. Cysteine residues on

In esophageal squamous cell carcinoma (ESCC), ACSL4 can serve as a valuable prognostic biomarker for long-term survival (Wang X

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These results illustrate that GGCT regulates intracellular ROS levels primarily via GSH rather than energy metabolism

doi: 10.1007/s11910-018-0882-y

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In addition to pyruvate-derived acetyl-CoA, -KG-derived metabolites (e.g., succinate and fumarate) generated via glutaminolysis are considered oncometabolites contributing to tumorigenesis 23