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Furthermore, excessive accumulation of NADH in conjunction with reduced NAD + availability can inhibit glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity in the glycolytic pathway, leading to glucose shunting to the glycolytic branch pathway (Yan et al., 2016

The intensification of modern livestock production systems means cattle sometimes cant meet their metabolic requirements from the level or quality of feed available, she says