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Following treatment, media was replaced with 80% (v/v) methanol (cooled to 80 C.) containing 500 nmol 6-chloronicotinamide (6-CN) as an internal standard (IS) to extract cellular metabolites

Bone and musculoskeletal research: Some work has extended into bone repair and osteoporosis models, where AOD9604 has shown early signs of supporting bone remodeling, though this area is less developed than its fat metabolism and cartilage research

Mohammadi EN, Louwies T, Pietra C, Northrup SR, Meerveld BG-V

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Natural: Synthetic cyanocobalamin requires conversion in the liver to become active, which means some people may not absorb it efficiently