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Consistent with the results acquired from PC cell lines, PDCs with low expression of VRK2 were more sensitive to APR-017 treatment than PDCs with high expression of VRK2 (Fig

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Sig Transduct Target Ther 5 , 227 (2020)

These results indicate that the substrate specificity of the latter differs fundamentally from that of its non-mammalian homologs

Among them, Selaginella moellendorffii has five, Picea sitchensis has four and Physcomitrella patens has two DJ-1/PfpI domain containing proteins (Table 1)