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High-fat diet-induced functional and pathologic changes in lacrimal gland

In this research, stimuli-responsive prodrug nanomedicines played a vital role as a drug delivery system, realizing tumor-specific therapy and reducing systemic toxicity by minimizing the exposure of healthy tissues to cytotoxic agents

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doi: 10.1016/S0031-6997(25)00462-4

In a trial involving 46 cancer patients, those who received selenium (200 mcg) and vitamin E (400 IU) had less cisplatin-induced kidney toxicity than those who received placebo (Hemati 2012)

Furthermore, the orphan nuclear receptor 77 can bind to the promoter region of eNOS, enhancing NO production