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Neoadjuvant immunotherapy for colorectal cancer: Right regimens, right patients, right directions

White and her associates listen and really care about getting to the root cause of an illness and not just about treating symptoms

To compare cellular versus whole-organismal metabolism, we tested glucose uptake and mitochondrial function, using 2-NBDG glucose uptake and MitoTracker Green multiplexed with MitoTracker Red CMXRos, as surrogate analyses for T cell metabolic fitness across conditions (Fig

Short trial periods on HU therapy ( 2 cm, portal fibrosis and irregular chelation history (class 1 = no risk factor, class 2 = one or two risk factors and class 3 = three risk factors)

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Third, individual variation is substantial: patients with severe insulin resistance or significant mitochondrial dysfunction may respond at lower doses than metabolically healthy athletes