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doi: 10.1213/ANE.0000000000002057 10

Xu J, Su X, Burley SK, Zheng XFS

The therapy for this ultra-rare disease uses a similar strategy to Intellias liver-targeting treatments for hATTR and HAE: it consists of a Cas12i2 nuclease and guide RNA encapsulated in a lipid nanoparticle (LNP)

Studies have shown that NOS knockout aggravates bleomycin (BLM)-induced fibrosis, whereas NO supplementation mitigates tissue damage [82]

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The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinsons disease