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Often referred to as the "master antioxidant," glutathione helps support the body's natural defense systems and protect cells from oxidative stress caused by free radicals

In the future, it is necessary to consider the integrating variables of hostmicrobiota interactions, and combine spatial metabolomics with single-cell transcriptomics to precisely locate polysaccharides targets in the intestinal tract, and achieve cellular-resolution mechanistic insights, thus providing a scientific foundation for their application within clinical settings and drug development

the retention times of all analyzed compounds are different

This illustration summarizes the key sources and consequences of ROS in MASLD

, (GSH) (GSSG), ,

We therefore suggest a mechanism that can be described according to the Cleland nomenclature as a combination of a random bi-uni mechanism and a ping-pong bi-bi (or uni-uni-uni-uni) mechanism in which the single product of the rate-limiting random mechanism becomes the first substrate of the ping-pong mechanism (Fig