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We averaged the prediction errors for duplicate molecules across multiple runs and classified each pKa site into one of the 18 functional groups we identified based on the GNNs internal sub-graph logic

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Glucose-dependent Insulinotropic Polypeptide (GIP) Receptor During fasting, K cells (found in the duodenum and jejunum) constitutively secrete the 42 amino acid protein GIP, which exhibits a marked increase in secretion after meals [11,12,13]

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GLP-1 agonists (Semaglutide, Tirzepatide) These FDA-approved medications have longer shelf life data

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Involucra los centros de integracin hipotalmicos: El hipotlamo funciona como el regulador principal de los ritmos circadianos, la sealizacin endocrina y el equilibrio autnomo

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Separation of soluble and insoluble components Single mouse hippocampal tissue was isolated, and 300 l mixed protein lysis solution with RIPA (Applygen, C1053), a protease inhibitor (Merck, 539134), and a phosphatase inhibitor (Merck, 524628) (=100:1:2) were added

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