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We find that Xpa-/- and Xpc-/- mouse livers accumulate mutations which we term SBS-NER-KO, a mutational signature resembling SBS8, which has an unknown mechanism but is likely driven by endogenous NER substrates

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10.21037/tau.2019.08.09 69 MontorsiF.OelkeM.HennegesC.BrockG.SaloniaA.dAnzeoG.et al (2016)

Specific BAs have been shown to directly influence the differentiation, activation, and effector functions of key innate and adaptive immune cell populations, highlighting a direct mechanistic link between microbial metabolism and anti-tumor immunity

All figures were subsequently manually refined (layout, labeling, and styling) and cross-checked against the manuscript to ensure accuracy and consistency

Free Radical Biological and Medicine