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Curcumin, a diarylheptanoid polyphenol from turmeric, inhibits CYP3A4, CYP1A2, and CYP2C9 isoenzymes at physiologically relevant concentrations

Higher total dose and the dose-to-weight ratio of the drug can potentially increase the possibility of LAST

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The difference was already present at three months and remained three months after treatment ended

doi: 10.1016/j.freeradbiomed.2023.10.015 87 WuJLiangJLiuRLvTFuKJiangLet al

Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer