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Systemic and metabolic conditions such as diabetes, obesity, multiple sclerosis, rheumatoid arthritis, lupus erythematosus, ankylosing spondylitis, as well as Alzheimers disease, Parkinsons disease, chronic depression and autism spectrum disorders also become a growing health problem [1,2,3,4,5,6]

Connective tissues include: Tendons Ligaments Fascia Cartilage support structures Skin matrix Joint-supporting tissues These tissues heal slowly because they often have limited blood supply

Dyes Pigment 208:110784

Protopanaxadiol is a natural compound that prevents glutamate-induced toxicity by improving mitochondrial function and enhancing anti-oxidant activity (Li et al., 2017)

Mizukami H, Osonoi S

Joerg E, Mederbek M, Emma K H, Clemens B, Felix J, Svenja M-W et al