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3.3.1 Stromal shielding and paracrine resistance signaling Cancer-associated fibroblasts (CAFs) represent a dominant stromal source of therapeutic resistance by simultaneously restricting drug delivery and activating bypass survival pathways (124)

found that the relative abundances of Streptococcus , Escherichia , Pseudoflavonifractor , Rothia , Granulicatella , Peptostreptococcus , and Actinomyces increased in AKI patients, whereas Gemmiger, Erysipelatoclostridium , Coprococcus , and Ruminococcus decreased[103]

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