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Given as individual agents to healthy rats, all dopamine antagonists (central [haloperidol (6.25 mg, 16 mg, 25 mg), fluphenazine (5 mg), levomepromazine (50 mg), chlorpromazine (10 mg), quetiapine (10 mg), olanzapine (5 mg), clozapine (100 mg), sulpiride (160 mg), metoclopramide (25 mg)) and peripheral(domperidone (10 mg)], l-NAME (5 mg) and l-arginine (100 mg) decreased the pressure within both sphincters

Ueno Y et al

doi: 10.1093/ajcn/nqz330 73 JoubertF.PuffN

Tamari R, McLornan DP, Ahn KW, Estrada-Merly N, Hernandez-Boluda JC, Giralt SA, Palmer JM, Gale RP, DeFilipp Z, Marks D, van der Poel MWM, Verdonck LF, Battiwalla M, Daz MA, Gupta V, Ali H, Litzow MR, Lazarus HM, Gergis U, Bashey A, Liesveld JL, Hashmi S, Pu JJ, Beitinjaneh A, Bredeson CN, Rizzieri DA, Savani BN, Abid MB, Ganguly S, Agrawal V, Ulrike V, Wirk B, Jain T, Cutler CS, Aljurf M, Kindwall-Keller T, Kharfan-Dabaja MA, Hildebrandt GC, Pawarode A, Solh MM, Yared JA, Grunwald MR, Nathan S, Nishihori T, Seo S, Scott BL, Nakamura R, Oran B, Czerw T, Yakoub-Agha I, Saber W Blood advances

However, their size poses limitations, requiring dedicated space and incurring costs for food, drugs, and surgical materials

Springer US, Boston, MA (1979)